Sometimes, you will get the following error after deploying your web application (developed for 64 bit
environment and if you referred to any GAC DLL in your application) on IIS 6 or IIS7.
Could not find the path of C:\Windows\assembly\GAC_MSIL_<Dll Name>_<GAC ID>\Bin
This error occurs because of your IIS currently not supporting 64bit applications, so you need to enable
the 64bit compatibility on IIS and you can resolve this by using the following steps on different IIS
versions based your requirements.
Step 1: Click Start, click Run, type cmd, and then click OK. Step 2: Type the following command to disable the 32-bit mode: cscript %SYSTEMDRIVE%\inetpub\adminscripts\adsutil.vbs SET W3SVC/AppPools/Enable32bitAppOnWin64 0 Step 3: Type the following command to install the version of ASP.NET 2.0 and to install the script maps at the IIS root and under: %SYSTEMROOT%\Microsoft.NET\Framework64\v2.0.50727 \aspnet_regiis.exe -i Step 4: Make sure that the status of ASP.NET version 2.0.50727 is set to Allowed in the Web service extension list in Internet Information Services Manager(if your application deployed on windows 2003 or 2008).For IIS7:
Step 1: Open the Internet Information Service Manager from Start Menu or Control Panel --> Administrative Tools. Step 2: Expand the Application Pools Node then find your Website Application Pool then right click on it then click on Advanced Settings, it will popup the settings screen here you need to set false for Enable32bitApplication. This settings may affect your existing 32bit application, if you get any error on your 32 applications then you reset the above setting and create a new application pool just like existing on and use itfor 64bit with appropriate Enable32bitApplication setting(value must be false).